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Why Naltrexone Works at First — and Why It Can Stop Working: An Addiction Specialist’s Perspective
Naltrexone is one of the most widely studied medications used in the treatment of alcohol use disorder. When paired with counseling and recovery support, it can reduce cravings and help people break the cycle of heavy drinking. But it’s also a medication that many people misunderstand. It works well for some, works briefly for others, and for a portion of people, it doesn’t work at all.
Harm Reduction in Alcohol Addiction: A Clinical Look at Naltrexone and Antabuse
Alcohol use disorder (AUD) remains one of the most pervasive and challenging conditions in addiction medicine. While abstinence-based models have long dominated treatment, harm reduction strategies—especially pharmacological interventions—are increasingly recognized for their ability to reduce cravings, prevent relapse, and support long-term recovery. Two FDA-approved medications stand out in this space: Naltrexone and Antabuse (Disulfiram).